Bridges Lab Journal Club

Papers Discussed in Journal Club

These are the papers that we discussed most recently in Journal club. Click here for the complete list.

    May 2020 Journal Club Articles

  • Plessow F, Singhal V, Toth AT, Micali N, Eddy KT, Misra M. Estrogen administration improves the trajectory of eating disorder pathology in oligo-amenorrheic athletes: A randomized controlled trial. Psychoneuroendocrinology 102: 273–280, 2019. 10.1016/j.psyneuen.2018.11.013. Discussed on May 15, 2020
  • Keleher MR, Erickson K, Kechris K, Yang I V., Dabelea D, Friedman JE, Boyle KE, Jansson T. Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort. Int. J. Obes. (2020). 10.1038/s41366-020-0574-y. Discussed on May 15, 2020
  • Hall KD, Guo J, Courville AB, Boring J, Brychta R, Kong Y, Darcey V, Forde CG, Gharib AM, Gallagher I, Howard R, Joseph P V, Milley L, Ouwerkerk R, Rozga I, Schick A, Stagliano M, Torres S, Chung ST. A plant-based, low-fat diet decreases ad libitum energy intake compared to an animal-based, ketogenic diet: An inpatient randomized controlled trial. NutRxiv (2020). doi: 10.31232/osf.io/rdjfb. 10.31232/osf.io/rdjfb. Discussed on May 15, 2020
  • Meddens SFW, de Vlaming R, Bowers P, Burik CAP, Linnér RK, Lee C, Okbay A, Turley P, Rietveld CA, Fontana MA, Ghanbari M, Imamura F, McMahon G, van der Most PJ, Voortman T, Wade KH, Anderson EL, Braun KVE, Emmett PM, Esko T, Gonzalez JR, Kiefte-de Jong JC, Langenberg C, Luan J, Muka T, Ring S, Rivadeneira F, Snieder H, van Rooij FJA, Wolffenbuttel BHR, Smith GD, Franco OH, Forouhi NG, Ikram MA, Uitterlinden AG, van Vliet-Ostaptchouk J V., Wareham NJ, Cesarini D, Harden KP, Lee JJ, Benjamin DJ, Chow CC, Koellinger PD. Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Mol. Psychiatry ( May 11, 2020). doi: 10.1038/s41380-020-0697-5. 10.1038/s41380-020-0697-5. Discussed on May 15, 2020
  • Orr SK, Dachner N, Frank L, Tarasuk V. Relation between household food insecurity and breastfeeding in Canada. Cmaj 190: E312–E319, 2018. 10.1503/cmaj.170880. Discussed on May 8, 2020
  • Strahm AM, Bagne AG, Rued HA, Larson KJ, Roemmich JN, Hilmert CJ. Prenatal traumatic stress and offspring hair cortisol concentration: A nine year follow up to the Red River flood pregnancy study. Psychoneuroendocrinology 113: 104579, 2020. 10.1016/j.psyneuen.2019.104579. Discussed on May 8, 2020
  • Tverdal A, Selmer R, Cohen JM, Thelle DS. Coffee consumption and mortality from cardiovascular diseases and total mortality: Does the brewing method matter? Eur. J. Prev. Cardiol. (2020). doi: 10.1177/2047487320914443. 10.1177/2047487320914443. Discussed on May 8, 2020
  • Norrelund H, Nair KS, Jorgensen JOL, Christiansen JS, Moller N. The Protein-Retaining Effects of Growth Hormone During Fasting Involve Inhibition of Muscle-Protein Breakdown. Diabetes 50: 96–104, 2001. 10.2337/diabetes.50.1.96. Discussed on May 8, 2020
  • Roumans KHM, Lindeboom L, Veeraiah P, Remie CME, Phielix E, Havekes B, Bruls YMH, Brouwers MCGJ, Ståhlman M, Alssema M, Peters HPF, de Mutsert R, Staels B, Taskinen MR, Borén J, Schrauwen P, Schrauwen-Hinderling VB. Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. Nat Commun 11: 1–11, 2020. 10.1038/s41467-020-15684-0. Discussed on May 1, 2020
  • Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JTJ, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O’Rahilly S. GDF15 mediates the effects of metformin on body weight and energy balance. Nature 578: 444–448, 2020. 10.1038/s41586-019-1911-y. Discussed on May 1, 2020

Comments on Papers

Owen Vaughn, Theresa Powell and Thomas Jansson. Glucocorticoid regulation of amino acid transport in primary human trophoblast cells 2019. Journal of Molecular Endocrinology 63(4):239-248 Full Text Our Thoughts Details.
Rachel Perry, Jon Resch, Amelia Douglass, Joseph Madara, Aviva Rabin-Court, Hakan Kucukdereli, Chen Wu, Joongyu Song, Bradford Lowell and Gerald Shulman. Leptin's hunger-suppressing effects are mediated by the hypothalamic-pituitary-adrenocortical axis in rodents 2019. Proceedings of the National Academy of Sciences 116(27):13670-13679 Full Text Our Thoughts Details.
Himsha Beltran, Vincente Perez-Garcia, Elena Fineberg, Robert Wilson, Alexander Murray, Cecilia Icoresi Mazzeo, Catherine Tudor, Arnold Sienerth, Jacqueline White, Elizabeth Tuck, Edward Ryder, Diane Gleason, Emma Siragher, Hannah Wardle-Jones, Nicole Staudt, Neha Wali, John Collins, Stefan Geyer, Elisabeth Busch-Nentwich, Antonella Galli, James Smith, Elizabeth Robertson, David Adams, Wolfgang Weninger, Timothy Mohun and Myriam Hemberger. Placentation defects are highly prevalent in embryonic lethal mouse mutants 2018. Nature 555(7697):463-468 Full Text Our Thoughts Details.
Morten Lyng Hogild, Ann Mosegaard Bak, Steen Bonlokke Pedersen, Jorgen Rungby, Jan Frystyk, Niels Moller, Niels Jessen and Jens Otto Lunde Jorgensen. Growth hormone signaling and action in obese versus lean human subjects 2019. American Journal of Physiology - Endocrinology and Metabolism 316(2):E333-E344 Full Text Our Thoughts Details.
Benjamin Hopkins, Chantal Pauli, Xing Du, Diana Wang, Xiang Li, David Wu, Solomon Amadiume, Marcus Goncalves, Cindy Hodakoski, Mark Lundquist, Rohan Bareja, Yan Ma, Emily Harris, Andrea Sboner, Himsha Beltran, Siddhartha Mukherjee and Lewis Cantley. Suppression of insulin feedback enhances the efficacy of PI3K inhibitors 2018. Nature 560(7719):499-503 Full Text Our Thoughts Details.
Graeme Lancaster, Katherine Langley, Nils Anton Berglund, Helene Kammoun, Saskia Reibe, Emma Estevez, Jacquelyn Weir, Natalie Mellett, Gerard Pernes, James Conway, Man Lee, Paul Timpson, Andrew Murphy, Seth Masters, Steve Gerondakis, Nenad Bartonicek, Dominik Kaczorowski, Marcel Dinger, Peter Meikle, Peter Bond and Mark Febbraio. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism 2018. Cell Metabolism Full Text Our Thoughts Details.
Choolson Jang, Sheng Hui, Wenyun Lu, Alexis Cowan, Raphael Morscher, Gina Lee, Wei Liu, Gregory Tesz, Morris Birnbaum and Joshua Rabinowitz. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids 2018. Cell Metabolism 27(2):351-361 Full Text Our Thoughts Details.
Naresh Bal, Santosh Maurya, Danesh Sopariwala, Sanjaya Sahoo, Subash Gupta, Sana Shaikh, Meghna Pant, Leslie Rowland, Eric Bombardier, Sanjeewa Goonasekera, Russel Tupling, Jeffery Molkentin and Muthu Periasamy. Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals. 2012. Nature Medicine 18(19):1575-9 Full Text Our Thoughts Details.
Kevin Hall, Thomas Bemis, Robert Brychta, Kong Chen, Amber Courvillle, Emma Crayner, Stephanie Goodwin, Juen Guo, Lillian Howard, Nicolas Knuth, Bernard Miller, Carla Prado, Maria Siervo, Monica Skarulis, Mary Walter, Peter Walter and Laura Yannai. Calorie for Calorie, Dietary Fat Restriction Results in More Body Fat Loss than Carbohydrate Restriction in People with Obesity 2015. Cell Metabolism 22(3):427-436 Full Text Our Thoughts Details.
Yumiko Oishi, Ichiro Manabe, Kazuyuki Tobe, Mitsuru Ohsugi, Tetsuya Kubota, Katsuhito Fujiu, Koji Maemura, Naoto Kubota, Takashi Kadowaki and Ryozo Nagai. SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta. 2008. Nature Medicine 14(6):656-666 Full Text Our Thoughts Details.
Andrew Shin, Martin Fasshauer, Nika Filatova, Linus Grundell, Elizabeth Zielinski, Jian-Ying Zhou, Thomas Scherer, Claudia Lindtner, Amanda Lapworth, Olga Ilkayeva, Uwe Knippschild, Anna Wolf, Ludger Shedja, Kevin Grove, Richard Smith, Wei-Jun Qian, Chrisopher Lynch, Christopher Newgard and Christophe Buettner. Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism. 2014. Cell metabolism S1550-4131(14):00400-8 Full Text Our Thoughts Details.
Jingxiang Huang, O. Nelson, Heiko Jansen, Elizabeth Galbreath, Kurt Morgenstern, Jamie Gehring, Kimberly Rigano, Jae Lee, Jianhua Gong, Adam Shaywitz, Chantal Vella, Charles Robbins and Kevin Corbit. Grizzly Bears Exhibit Augmented Insulin Sensitivity while Obese Prior to a Reversible Insulin Resistance during Hibernation 2014. Cell Metabolism 20(2):376-82 Full Text Our Thoughts Details.
Robert Koza, Larissa Nikonova, Jessica Hogan, Jong-Seop Rim, Tamra Mendoza, Christopher Faulk, Jihad Skaf and Leslie Kozak. Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. 2006. PLOS Genetics 2(5):e81 Full Text Our Thoughts Details.
Xiaoyuan Xu, Ambar Grijalva, Alicja Skowronski, Marco van Eijk, Mireille J Serlie and Anthony Ferrante. Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation. 2014. Cell metabolism 18(6):816-30 Full Text Our Thoughts Details.
Hui Zhang, Jingxiang Huang, Katrin Düvel, Bernard Boback, Shulin Wu, Rachel Squillace, Chin-Lee Wu and Brendan Manning. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. 2009. PLOS One 4(7):e6189 Full Text Our Thoughts Details.
Alexander von Wilamowitz-Moellendorff, Roger Hunter, Mar Garcia-Rocha, Li Kang, Iliana Lopez-Soldado, Louise Lantier, Kashyap Patel, Mark Peggie, Carlos Martinez-Pons, Martin Voss, Joaquim Calbo, Patricia Cohen, David Wasserman, Joan Guinovart and Kei Sakamoto. Glucose-6-Phosphate-Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis. 2013. Diabetes Full Text Our Thoughts Details.
Christine Longuet, Elaine Sinclair, Adriano Maida, Laurie Baggio, Marlena Maziarz, Maureen Charron and Daniel Drucker. The glucagon receptor is required for the adaptive metabolic response to fasting. 2008. Cell Metabolism 8(5):359-71 Full Text Our Thoughts Details.
Subhash Katewa, Fabio Demontis, Marysia Kolipinski, Alan Hubbard, Matthew Gill, Norbert Perrimon, Simon Melov and Pankaj Kapahi. Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. 2012. Cell metabolism 16(1):97-103 Full Text Our Thoughts Details.
Shunsuke Takasuga, Yasuo Horie, Junko Sasaki, Ge-Hong Sun-Wada, Nobuyuki Kawamura, Ryota Iizuka, Katsunori Mizuno, Satoshi Eguchi, Satoshi Kofuji, Hirotaka Kimura, Masakazu Yamazaki, Chihoko Horie, Eri Odanaga, Yoshiko Sato, Shinsuke Chida, Kenji Kontani, Akihiro Harada, Akihiro Katada, Akira Suzuki, Yoh Wada, Hirohide Ohnishi and Takehiko Sasaki. Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. 2013. Proceedings of the National Academy of Sciences of the United States of America 110(5):1726-31 Full Text Our Thoughts Details.