Bridges Lab Journal Club Articles

2025 Journal Club Articles

  • O'Sullivan EJ, Perrine CG, Rasmussen KM. Early Breastfeeding Problems Mediate the Negative Association between Maternal Obesity and Exclusive Breastfeeding at 1 and 2 Months Postpartum. J Nutr. 2015 Oct;145(10):2369-78. doi: 10.3945/jn.115.214619. Epub 2015 Aug 19. PMID: 26290005; PMCID: PMC4592473. Publisher Link

    Nov. 20, 2025

  • Horvath D, Mink D, Saxena K, Inholz K, Wirtz PH, Basler M. Stress transmission in social groups of mice: unveiling physiological responses, behavioral patterns, and immune dynamics. iScience. 2025 May 27;28(6):112769. doi: 10.1016/j.isci.2025.112769. PMID: 40546941; PMCID: PMC12178794. Publisher Link

    Nov. 6, 2025

  • Gao Y, Kennelly JP, Xiao X, Whang E, Ferrari A, Bedard AH, Mack JJ, Nguyen A, Srikanth S, Weston T, Uchiyama LF, Cohn W, Cho DH, Lee MS, Whitelegge J, Gwack Y, Young SG, Bensinger SJ, Tontonoz P. T cell cholesterol transport links intestinal immune responses to dietary lipid absorption. Science. 2025 Oct 9;390(6769):eadt4169. doi: 10.1126/science.adt4169. Epub 2025 Oct 9. PMID: 41066556. Publisher Link

    Oct. 16, 2025

  • Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nat Commun. 2021 Jan 11;12(1):213. doi: 10.1038/s41467-020-20500-w. PMID: 33431899; PMCID: PMC7801461. Publisher Link

    Oct. 2, 2025

  • Jones JM, Reinke SN, Mousavi-Derazmahalleh M, Garssen J, Jenmalm MC, Srinivasjois R, Silva D, Keelan J, Prescott SL, Palmer DJ, Christophersen CT. Maternal prebiotic supplementation during pregnancy and lactation modifies the microbiome and short chain fatty acid profile of both mother and infant. Clin Nutr. 2024 Apr;43(4):969-980. doi: 10.1016/j.clnu.2024.02.030. Epub 2024 Mar 1. PMID: 38452522. Publisher Link

    April 4, 2025

  • Pinckaers PJ, Domi? J, Petrick HL, Holwerda AM, Trommelen J, Hendriks FK, Houben LH, Goessens JP, van Kranenburg JM, Senden JM, de Groot LC, Verdijk LB, Snijders T, van Loon LJ. Higher Muscle Protein Synthesis Rates Following Ingestion of an Omnivorous Meal Compared with an Isocaloric and Isonitrogenous Vegan Meal in Healthy, Older Adults. J Nutr. 2024 Jul;154(7):2120-2132. doi: 10.1016/j.tjnut.2023.11.004. Epub 2023 Nov 15. PMID: 37972895. Publisher Link

    March 14, 2025

  • Zhao Q, Yokomizo S, Perle SJ, Lee YF, Zhou H, Miller MR, Li H, Gerashchenko D, Gomperts SN, Bacskai BJ, Kastanenka KV. Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model. Sci Rep. 2024 Oct 4;14(1):23044. doi: 10.1038/s41598-024-73082-8. PMID: 39362954; PMCID: PMC11450172. Publisher Link

    Feb. 12, 2025

  • Reed JN, Hasan F, Karkar A, Banka D, Hinkle J, Shastri P, Srivastava N, Scherping SC, Newkirk SE, Ferris HA, Kundu BK, Kranz S, Civelek M, Keller SR. Combined effects of genetic background and diet on mouse metabolism and gene expression. iScience. 2024 Nov 4;27(12):111323. doi: 10.1016/j.isci.2024.111323. PMID: 39640571; PMCID: PMC11617257. Publisher Link

    Jan. 29, 2025

    • 2024 Journal Club Articles

  • Huang S, Chen J, Cui Z, Ma K, Wu D, Luo J, Li F, Xiong W, Rao S, Xiang Q, Shi W, Song T, Deng J, Yin Y, Tan C. Lachnospiraceae-derived butyrate mediates protection of high fermentable fiber against placental inflammation in gestational diabetes mellitus. Sci Adv. 2023 Nov 3;9(44):eadi7337. doi: 10.1126/sciadv.adi7337. Epub 2023 Nov 3. PMID: 37922350; PMCID: PMC10624355. Publisher Link

    Nov. 11, 2024

  • Machado H, Hofer P, Zechner R, Smith TK, Figueiredo LM. Adipocyte lipolysis protects mice against Trypanosoma brucei infection. Nat Microbiol. 2023 Nov;8(11):2020-2032. doi: 10.1038/s41564-023-01496-7. Epub 2023 Oct 12. PMID: 37828246; PMCID: PMC10627827. Publisher Link

    Oct. 28, 2024

  • Sonsalla MM, Babygirija R, Johnson M, Cai S, Cole M, Yeh CY, Grunow I, Liu Y, Vertein D, Calubag MF, Trautman ME, Green CL, Rigby MJ, Puglielli L, Lamming DW. Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease. Geroscience. 2024 Sep 14. doi: 10.1007/s11357-024-01337-3. Epub ahead of print. PMID: 39271570. Publisher Link

    Sept. 30, 2024

  • Bolognini, D., Halgren, A., Lou, R.N. et al. Recurrent evolution and selection shape structural diversity at the amylase locus. Nature (2024). Publisher Link

    Sept. 16, 2024

  • Crujeiras AB, Izquierdo AG, Primo D, Milagro FI, Sajoux I, Jácome A, Fernandez-Quintela A, Portillo MP, Martínez JA, Martinez-Olmos MA, de Luis D, Casanueva FF. Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity. Clin Nutr. 2021 Jun;40(6):3959-3972. doi: 10.1016/j.clnu.2021.05.010. Epub 2021 May 21. PMID: 34139469. Publisher Link

    April 5, 2024

  • Ryan JP, Karim HT, Aizenstein HJ, Helbling NL, Toledo FGS. Insulin sensitivity predicts brain network connectivity following a meal. Neuroimage. 2018 May 1;171:268-276. doi: 10.1016/j.neuroimage.2018.01.024. Epub 2018 Jan 13. PMID: 29339315; PMCID: PMC5857474. Publisher Link

    March 29, 2024

  • Berry A, Collacchi B, Capoccia S, D'Urso MT, Cecchetti S, Raggi C, Sestili P, Aricò E, Pontecorvi G, Puglisi R, Ortona E, Cirulli F. Chronic Isolation Stress Affects Central Neuroendocrine Signaling Leading to a Metabolically Active Microenvironment in a Mouse Model of Breast Cancer. Front Behav Neurosci. 2021 Jul 9;15:660738. doi: 10.3389/fnbeh.2021.660738. PMID: 34305544; PMCID: PMC8298821. Publisher Link

    March 22, 2024

  • Moore MP, Shryack G, Alessi I, Wieschhaus N, Meers GM, Johnson SA, Wheeler AA, Ibdah JA, Parks EJ, Rector RS. Relationship Between Serum ?-Hydroxybutyrate and Hepatic Fatty Acid Oxidation in Individuals with Obesity and NAFLD. Am J Physiol Endocrinol Metab. 2024 Feb 21. doi: 10.1152/ajpendo.00336.2023. Epub ahead of print. PMID: 38381399. Publisher Link

    March 15, 2024

  • Lu JF, Zhu MQ, Xia B, Zhang NN, Liu XP, Liu H, Zhang RX, Xiao JY, Yang H, Zhang YQ, Li XM, Wu JW. GDF15 is a major determinant of ketogenic diet-induced weight loss. Cell Metab. 2023 Dec 5;35(12):2165-2182.e7. doi: 10.1016/j.cmet.2023.11.003. Erratum in: Cell Metab. 2024 Feb 6;36(2):454-456. PMID: 38056430. Publisher Link

    Feb. 23, 2024

  • Price TR, Emfinger CH, Schueler KL, King S, Nicholson R, Beck T, Yandell BS, Summers SA, Holland WL, Krauss RM, Keller MP, Attie AD. Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population. J Lipid Res. 2023 Dec;64(12):100471. doi: 10.1016/j.jlr.2023.100471. Epub 2023 Nov 7. PMID: 37944753; PMCID: PMC10750189. Publisher Link

    Feb. 16, 2024

  • Trommelen J, van Lieshout GAA, Nyakayiru J, Holwerda AM, Smeets JSJ, Hendriks FK, van Kranenburg JMX, Zorenc AH, Senden JM, Goessens JPB, Gijsen AP, van Loon LJC. The anabolic response to protein ingestion during recovery from exercise has no upper limit in magnitude and duration in vivo in humans. Cell Rep Med. 2023 Dec 19;4(12):101324. doi: 10.1016/j.xcrm.2023.101324. PMID: 38118410; PMCID: PMC10772463. Publisher Link

    Feb. 9, 2024

  • McClean PL, Hölscher C. Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease. Neuropharmacology. 2014 Jan;76 Pt A:57-67. doi: 10.1016/j.neuropharm.2013.08.005. Epub 2013 Aug 21. PMID: 23973293. Publisher Link

    Feb. 2, 2024

  • Soták M, Casselbrant A, Rath E, Zietek T, Strömstedt M, Adingupu DD, Karlsson D, Fritsch Fredin M, Ergang P, Pácha J, Batorsky A, Alpers CE, Börgeson E, Hansen PBL, Ericsson A, Björnson Granqvist A, Wallenius V, Fändriks L, Unwin RJ. Intestinal sodium/glucose cotransporter 3 expression is epithelial and downregulated in obesity. Life Sci. 2021 Feb 15;267:118974. doi: 10.1016/j.lfs.2020.118974. Epub 2020 Dec 30. PMID: 33385407. Publisher Link

    Jan. 26, 2024

  • O'Donnell MG, Stumpp L, Gallaher MJ, Powers RW. Pre-pregnancy stress induces maternal vascular dysfunction during pregnancy and postpartum. Reprod Sci. 2023 Nov;30(11):3197-3211. doi: 10.1007/s43032-023-01248-2. Epub 2023 May 23. PMID: 37219786; PMCID: PMC10204668. Publisher Link

    Jan. 19, 2024

    • 2023 Journal Club Articles

  • Mey JT, Vandagmansar B, Dantas WS, Belmont KP, Axelrod CL, Kirwan JP. Ketogenic propensity is differentially related to lipid-induced hepatic and peripheral insulin resistance. Acta Physiol (Oxf). 2023 Dec;239(4):e14054. doi: 10.1111/apha.14054. Epub 2023 Oct 16. PMID: 37840478. Publisher Link

    Dec. 1, 2023

  • Gupta DK, Lewis CE, Varady KA, Su YR, Madhur MS, Lackland DT, Reis JP, Wang TJ, Lloyd-Jones DM, Allen NB. Effect of Dietary Sodium on Blood Pressure: A Crossover Trial. JAMA. 2023 Nov 11:e2323651. doi: 10.1001/jama.2023.23651. Epub ahead of print. PMID: 37950918; PMCID: PMC10640704. Publisher Link

    Nov. 24, 2023

  • Wang KC, Woung LC, Tsai MT, Liu CC, Su YH, Li CY. Risk of Alzheimer's disease in relation to diabetes: a population-based cohort study. Neuroepidemiology. 2012;38(4):237-44. doi: 10.1159/000337428. Epub 2012 May 5. PMID: 22572745. Publisher Link

    Nov. 10, 2023

  • Murray AJ, Knight NS, Cochlin LE, McAleese S, Deacon RM, Rawlins JN, Clarke K. Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding. FASEB J. 2009 Dec;23(12):4353-60. doi: 10.1096/fj.09-139691. Epub 2009 Aug 10. PMID: 19667117. Publisher Link

    Nov. 3, 2023

  • Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK. Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. Lancet. 2017 Feb 25;389(10071):834-845. doi: 10.1016/S0140-6736(16)31714-7. Epub 2017 Jan 12. Erratum in: Lancet. 2017 Feb 25;389(10071):804. Erratum in: Lancet. 2017 Feb 25;389(10071):804. PMID: 28088338; PMCID: PMC7864285. Publisher Link

    Oct. 20, 2023

  • Norwitz NG, Feldman D, Soto-Mota A, Kalayjian T, Ludwig DS. Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype. Curr Dev Nutr. 2021 Nov 30;6(1):nzab144. doi: 10.1093/cdn/nzab144. PMID: 35106434; PMCID: PMC8796252. Publisher Link

    Oct. 13, 2023

  • Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrision B, Rothstein JD, Khvorova A, Czech MP. Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis. bioRxiv [Preprint]. 2023 Oct 19:2023.05.03.539244. doi: 10.1101/2023.05.03.539244. PMID: 37205462; PMCID: PMC10187148. Publisher Link

    Sept. 29, 2023

  • Wolters FJ, Chibnik LB, Waziry R, Anderson R, Berr C, Beiser A, Bis JC, Blacker D, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Davis-Plourde KL, de Wolf F, Debette S, Dufouil C, Fornage M, Goudsmit J, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Joas E, Kern S, Kuller LH, Launer L, Lopez OL, Matthews FE, McRae-McKee K, Meirelles O, Mosley TH Jr, Pase MP, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Wetterberg H, Wong MM, Zettergren A, Hofman A. Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium. Neurology. 2020 Aug 4;95(5):e519-e531. doi: 10.1212/WNL.0000000000010022. Epub 2020 Jul 1. PMID: 32611641; PMCID: PMC7455342. Publisher Link

    Sept. 22, 2023

  • Abi-Ghanem C, Salinero AE, Kordit D, Mansour FM, Kelly RD, Venkataganesh H, Kyaw NR, Gannon OJ, Riccio D, Fredman G, Poitelon Y, Belin S, Kopec AM, Robison LS, Zuloaga KL. Sex differences in the effects of high fat diet on underlying neuropathology in a mouse model of VCID. Biol Sex Differ. 2023 May 19;14(1):31. doi: 10.1186/s13293-023-00513-y. PMID: 37208759; PMCID: PMC10199629. Publisher Link

    Sept. 15, 2023

  • Chiba T, Takaguri A, Kooka A, Kowatari K, Yoshizawa M, Fukushi Y, Hongo F, Sato H, Fujisawa M, Wada S, Maeda T. Suppression of milk-derived miR-148a caused by stress plays a role in the decrease in intestinal ZO-1 expression in infants. Clin Nutr. 2022 Dec;41(12):2691-2698. doi: 10.1016/j.clnu.2022.10.004. Epub 2022 Oct 13. PMID: 36343560. Publisher Link

    Sept. 8, 2023

  • Miyamoto J, Ohue-Kitano R, Mukouyama H, Nishida A, Watanabe K, Igarashi M, Irie J, Tsujimoto G, Satoh-Asahara N, Itoh H, Kimura I. Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23813-23821. Publisher Link

    Sept. 1, 2023

  • Linden MA, Burke SJ, Pirzadah HA, Huang TY, Batdorf HM, Mohammed WK, Jones KA, Ghosh S, Campagna SR, Collier JJ, Noland RC. Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration. Mol Metab. 2023 Aug;74:101751. Publisher Link

    Aug. 25, 2023

  • Fu X, Fletcher JA, Deja S, Inigo-Vollmer M, Burgess SC, Browning JD. Persistent fasting lipogenesis links impaired ketogenesis with citrate synthesis in humans with nonalcoholic fatty liver. J Clin Invest. 2023 May 1;133(9):e167442 Publisher Link

    March 23, 2023

    • 2022 Journal Club Articles

  • Shannon, C. E., Merovci, A., Fourcaudot, M., Tripathy, D., Abdul-Ghani, M., Wang, H., Han, X., Norton, L., and DeFronzo, R. A. (2022) Effects of Sustained Hyperglycemia on Skeletal Muscle Lipids in Healthy Subjects. J. Clin. Endocrinol. Metab. In Press, 1–10 Publisher Link

    June 10, 2022

  • Kalafut, K. C., Mitchell, S. J., MacArthur, M. R., and Mitchell, J. R. (2022) Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction. Front. Nutr. 9, 1–12 Publisher Link

    June 3, 2022

  • Dukay-Szabó, S., Simon, D., Varga, M., Koller, O., Pataki, Z., Rigó, J., and Túry, F. (2022) The applicability of the Eating Disorder Inventory in pregnancy. Eat. Weight Disord. 27, 629–637 Publisher Link

    May 6, 2022

  • Díaz, M., Campderrós, L., Guimaraes, M. P., López-Bermejo, A., de Zegher, F., Villarroya, F., and Ibáñez, L. (2020) Circulating growth-and-differentiation factor-15 in early life: relation to prenatal and postnatal growth and adiposity measurements. Pediatr. Res. 87, 897–902 Publisher Link

    April 15, 2022

  • Solmonson, A., Faubert, B., Gu, W., Rao, A., Cowdin, M. A., Menendez-Montes, I., Kelekar, S., Rogers, T. J., Pan, C., Guevara, G., Tarangelo, A., Zacharias, L. G., Martin-Sandoval, M. S., Do, D., Pachnis, P., Dumesnil, D., Mathews, T. P., Tasdogan, A., Pham, A., Cai, L., Zhao, Z., Ni, M., Cleaver, O., Sadek, H. A., Morrison, S. J., and DeBerardinis, R. J. (2022) Compartmentalized metabolism supports midgestation mammalian development. Nature. 604, 349–353 Publisher Link

    April 8, 2022

  • Edwards, M. A., Muraleedharan, D., and Spaulding, A. (2022) Racial disparities in reasons for mortality following bariatric surgery. J. Racial Ethn. Heal. Disparities. 10.1007/s40615-022-01242-5 Publisher Link

    April 1, 2022

  • Sharma, A. J., Bulkley, J. E., Stoneburner, A. B., Dandamudi, P., Leo, M., Callaghan, W. M., and Vesco, K. K. (2021) Bias in Self-reported Prepregnancy Weight Across Maternal and Clinical Characteristics. Matern. Child Health J. 25, 1242–1253 Publisher Link

    March 25, 2022

  • Chaix, A., Deota, S., Bhardwaj, R., Lin, T., and Panda, S. (2021) Sex- and age-dependent outcomes of 9-hour time-restricted feeding of a Western high-fat high-sucrose diet in C57BL/6J mice. Cell Rep. 36, 109543 Publisher Link

    March 18, 2022

    • 2020 Journal Club Articles

  • Plessow F, Singhal V, Toth AT, Micali N, Eddy KT, Misra M. Estrogen administration improves the trajectory of eating disorder pathology in oligo-amenorrheic athletes: A randomized controlled trial. Psychoneuroendocrinology 102: 273–280, 2019. Publisher Link

    May 15, 2020

  • Keleher MR, Erickson K, Kechris K, Yang I V., Dabelea D, Friedman JE, Boyle KE, Jansson T. Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort. Int. J. Obes. (2020). Publisher Link

    May 15, 2020

  • Hall KD, Guo J, Courville AB, Boring J, Brychta R, Kong Y, Darcey V, Forde CG, Gharib AM, Gallagher I, Howard R, Joseph P V, Milley L, Ouwerkerk R, Rozga I, Schick A, Stagliano M, Torres S, Chung ST. A plant-based, low-fat diet decreases ad libitum energy intake compared to an animal-based, ketogenic diet: An inpatient randomized controlled trial. NutRxiv (2020). doi: 10.31232/osf.io/rdjfb. Publisher Link

    May 15, 2020

  • Meddens SFW, de Vlaming R, Bowers P, Burik CAP, Linnér RK, Lee C, Okbay A, Turley P, Rietveld CA, Fontana MA, Ghanbari M, Imamura F, McMahon G, van der Most PJ, Voortman T, Wade KH, Anderson EL, Braun KVE, Emmett PM, Esko T, Gonzalez JR, Kiefte-de Jong JC, Langenberg C, Luan J, Muka T, Ring S, Rivadeneira F, Snieder H, van Rooij FJA, Wolffenbuttel BHR, Smith GD, Franco OH, Forouhi NG, Ikram MA, Uitterlinden AG, van Vliet-Ostaptchouk J V., Wareham NJ, Cesarini D, Harden KP, Lee JJ, Benjamin DJ, Chow CC, Koellinger PD. Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Mol. Psychiatry ( May 11, 2020). doi: 10.1038/s41380-020-0697-5. Publisher Link

    May 15, 2020

  • Orr SK, Dachner N, Frank L, Tarasuk V. Relation between household food insecurity and breastfeeding in Canada. Cmaj 190: E312–E319, 2018. Publisher Link

    May 8, 2020

  • Strahm AM, Bagne AG, Rued HA, Larson KJ, Roemmich JN, Hilmert CJ. Prenatal traumatic stress and offspring hair cortisol concentration: A nine year follow up to the Red River flood pregnancy study. Psychoneuroendocrinology 113: 104579, 2020. Publisher Link

    May 8, 2020

  • Tverdal A, Selmer R, Cohen JM, Thelle DS. Coffee consumption and mortality from cardiovascular diseases and total mortality: Does the brewing method matter? Eur. J. Prev. Cardiol. (2020). doi: 10.1177/2047487320914443. Publisher Link

    May 8, 2020

  • Norrelund H, Nair KS, Jorgensen JOL, Christiansen JS, Moller N. The Protein-Retaining Effects of Growth Hormone During Fasting Involve Inhibition of Muscle-Protein Breakdown. Diabetes 50: 96–104, 2001. Publisher Link

    May 8, 2020

  • Roumans KHM, Lindeboom L, Veeraiah P, Remie CME, Phielix E, Havekes B, Bruls YMH, Brouwers MCGJ, Ståhlman M, Alssema M, Peters HPF, de Mutsert R, Staels B, Taskinen MR, Borén J, Schrauwen P, Schrauwen-Hinderling VB. Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. Nat Commun 11: 1–11, 2020. Publisher Link

    May 1, 2020

  • Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JTJ, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O’Rahilly S. GDF15 mediates the effects of metformin on body weight and energy balance. Nature 578: 444–448, 2020. Publisher Link

    May 1, 2020

  • Chowdhury EA, Richardson JD, Tsintzas K, Thompson D, Betts JA. Carbohydrate-rich breakfast attenuates glycaemic, insulinaemic and ghrelin response to ad libitum lunch relative to morning fasting in lean adults. Br J Nutr 114: 98–107, 2015. Publisher Link

    May 1, 2020

  • Murphy C, Koehler K. Caloric restriction induces anabolic resistance to resistance exercise. Eur J Appl Physiol 120: 1155–1164, 2020. Publisher Link

    May 1, 2020

  • Stratton MT, Tinsley GM, Alesi MG, Hester GM, Olmos AA, Serafini PR, Modjeski AS, Mangine GT, King K, Savage SN, Webb AT, VanDusseldorp TA. Four Weeks of Time-Restricted Feeding Combined with Resistance Training Does Not Differentially Influence Measures of Body Composition, Muscle Performance, Resting Energy Expenditure, and Blood Biomarkers. Nutrients 12: 1126, 2020. Publisher Link

    April 24, 2020

  • O’Brien KM, Tronick EZ, Moore CL. Relationship between hair cortisol and perceived chronic stress in a diverse sample. Stress Heal 29: 337–344, 2013. Publisher Link

    April 24, 2020

  • Lau C, Hurst NM, Smith EO, Schanler RJ. Ethnic/racial diversity, maternal stress, lactation and very low birthweight infants. J Perinatol 27: 399–408, 2007. Publisher Link

    April 24, 2020

  • Raymond J, Morin A, Plamondon H. Delivery method matters: omega-3 supplementation by restricted feeding period and oral gavage has a distinct impact on corticosterone secretion and anxious behavior in adolescent rats. Nutr Neurosci 0: 1–11, 2020. Publisher Link

    April 24, 2020

  • Schnurr TM, Jakupovi H, Carrasquilla GD, Ängquist L, Grarup N, Sørensen TIA, Tjønneland A, Overvad K, Pedersen O, Hansen T, Kilpeläinen TO. Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study. Diabetologia ( April 15, 2020). Publisher Link

    April 17, 2020

  • Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, Erhardt A, Binder EB, Mehta D. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: Relevance of glucocorticoid signaling. Genome Biol 16: 1–12, 2015. Publisher Link

    April 17, 2020

  • Otsuka H, Kimura T, Ago Y, Nakama M, Aoyama Y, Abdelkreem E, Matsumoto H, Ohnishi H, Sasai H, Osawa M, Yamaguchi S, Mitchell GA, Fukao T. Deficiency of 3-hydroxybutyrate dehydrogenase (BDH1) in mice causes low ketone body levels and fatty liver during fasting. J Inherit Metab Dis 1: 2–31, 2020. Publisher Link

    April 17, 2020

  • Higgins KA, Considine R V., Mattes RD. Aspartame consumption for 12 weeks does not affect glycemia, appetite, or body weight of healthy, lean adults in a randomized controlled trial. J Nutr 148: 650–657, 2018. Publisher Link

    April 3, 2020

  • Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. The proximal origin of SARS-CoV-2. Nat Med 89: 44–48, 2020. Publisher Link

    April 3, 2020

  • Markova M, Koelman L, Hornemann S, Pivovarova O, Sucher S, Machann J, Rudovich N, Thomann R, Schneeweiss R, Rohn S, Pfeiffer AFH, Aleksandrova K. Effects of plant and animal high protein diets on immune-inflammatory biomarkers: A 6-week intervention trial. Clin Nutr 39: 862–869, 2020. Publisher Link

    April 3, 2020

  • Sugawara J, Iwama N, Hoshiai T, Tokunaga H, Nishigori H, Metoki H, Okamura K, Yaegashi N. Regional Birth Outcomes after the 2011 Great East Japan Earthquake and Tsunami in Miyagi Prefecture. Prehosp Disaster Med : 1–5, 2018. Publisher Link

    April 3, 2020

  • Badman MK, Kennedy AR, Adams ACC, Pissios P, Maratos-flier E. A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss. Am J Physiol - Endocrinol Metab 297: 1197–1204, 2009. Publisher Link

    March 27, 2020

  • Heikura IA, Burke LM, Hawley JA, Ross ML, Garvican-Lewis L, Sharma AP, McKay AKA, Leckey JJ, Welvaert M, McCall L, Ackerman KE. A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise. Front Endocrinol (Lausanne) 10: 1–10, 2020. Publisher Link

    March 27, 2020

  • Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BJM, Evans-Molina C, Mirmira. RG, Metz TO. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab 31: 363-374.e6, 2020. Publisher Link

    March 27, 2020

  • Nakayasu ES, Syed F, Tersey SA, Gritsenko MA, Mitchell HD, Chan CY, Dirice E, Turatsinze JV, Cui Y, Kulkarni RN, Eizirik DL, Qian WJ, Webb-Robertson BJM, Evans-Molina C, Mirmira. RG, Metz TO. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention. Cell Metab 31: 363-374.e6, 2020. Publisher Link

    March 20, 2020

  • Lagström H, Rautava S, Ollila H, Kaljonen A, Turta O, Mäkelä J, Yonemitsu C, Gupta J, Bode L. Associations between human milk oligosaccharides and growth in infancy and early childhood. Am. J. Clin. Nutr. (2020). Publisher Link

    March 20, 2020

  • Bedford JR, Ivermee CL, Lange K, Chapman MJ. Nutrition and functional outcomes after critical illness due to pandemic (H1N1) 2009 influenza: A retrospective cohort study. Crit Care Resusc 13: 226–231, 2011. Publisher Link

    March 20, 2020

  • Upadhyay A, Sinha RA, Kumar A, Godbole MM. Time-restricted feeding ameliorates maternal high-fat diet-induced fetal lung injury. Exp Mol Pathol 114: 104413, 2020. Publisher Link

    March 20, 2020

  • Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, Lusis AJ. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell 151: 658–670, 2012. Publisher Link

    March 13, 2020

  • Ramsay DT, Kent JC, Hartmann RA, Hartmann PE. Anatomy of the lactating human breast redefined with ultrasound imaging. J Anat 206: 525–534, 2005. Publisher Link

    March 13, 2020

  • Richter J, Herzog N, Janka S, Baumann T, Kistenmacher A, Oltmanns KM. Twice as High Diet-Induced Thermogenesis After Breakfast vs Dinner On High-Calorie as Well as Low-Calorie Meals. J Clin Endocrinol Metab 105: 1–11, 2020. Publisher Link

    March 13, 2020

  • McCleary-Gaddy AT, Miller CT, Grover KW, Hodge JJ, Major B. Weight Stigma and Hypothalamic-Pituitary-Adrenocortical Axis Reactivity in Individuals Who Are Overweight. Ann Behav Med 53: 392–398, 2019. Publisher Link

    Feb. 14, 2020

  • Hollenbach JP, Kuo CL, Mu J, Gerrard M, Gherlone N, Sylvester F, Ojukwu M, Cloutier MM. Hair cortisol, perceived stress, and social support in mother–child dyads living in an urban neighborhood. Stress 22: 632–639, 2019. Publisher Link

    Feb. 14, 2020

  • Curtis PJ, Van Der Velpen V, Berends L, Jennings A, Feelisch M, Umpleby AM, Evans M, Fernandez BO, Meiss MS, Minnion M, Potter J, Minihane AM, Kay CD, Rimm EB, Cassidy A. Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial. Am J Clin Nutr 109: 1535–1545, 2019. Publisher Link

    Feb. 14, 2020

  • Liko D, Rzepiela A, Vukojevic V, Zavolan M, Hall MN. Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs . Proc. Natl. Acad. Sci. (2020). Publisher Link

    Feb. 7, 2020

  • Timmers S, De Vogel-Van Den Bosch J, De Wit N, Schaart G, Van Beurden D, Hesselink M, Van Der Meer R, Schrauwen P. Differential effects of saturated versus unsaturated dietary fatty acids on weight gain and myocellular lipid profiles in mice. Nutr Diabetes 1: e11-9, 2011. Publisher Link

    Feb. 7, 2020

  • Natividade da Silva F, Brunetta HS, Bruxel MA, Gomes FA, Rafacho A. Impact of glucocorticoid treatment before pregnancy on glucose homeostasis of offspring exposed to glucocorticoid in adult life. Life Sci 237: 116913, 2019. Publisher Link

    Feb. 7, 2020

  • Epel ES, Hartman A, Jacobs LM, Leung C, Cohn MA, Jensen L, Ishkanian L, Wojcicki J, Mason AE, Lustig RH, Stanhope KL, Schmidt LA. Association of a Workplace Sales Ban on Sugar-Sweetened Beverages with Employee Consumption of Sugar-Sweetened Beverages and Health. JAMA Intern Med 180: 9–16, 2020. Publisher Link

    Feb. 7, 2020

  • Adamovich Y, Rousso-Noori L, Zwighaft Z, Neufeld-Cohen A, Golik M, Kraut-Cohen J, Wang M, Han X, Asher G. Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell Metab 19: 319–330, 2014. Publisher Link

    Jan. 31, 2020

  • Gilbertson HR, Brand-Miller JC, Thorburn AW, Evans S, Chondros P, Werther GA. The Effect of Flexible Low Glycemic Index Dietary Advice Versus Measured Carbohydrate Exchange Diets on Glycemic Control in Children With Type 1 Diabetes. Diabetes Care 24: 1137–1143, 2001. Publisher Link

    Jan. 31, 2020

  • D’Anna-Hernandez KL, Ross RG, Natvig CL, Laudenslager ML. Hair cortisol levels as a retrospective marker of hypothalamic-pituitary axis activity throughout pregnancy: Comparison to salivary cortisol. Physiol Behav 104: 348–353, 2011. Publisher Link

    Jan. 31, 2020

  • Gil CI, Ost M, Kasch J, Schumann S, Heider S, Klaus S. Role of GDF15 in active lifestyle induced metabolic adaptations and acute exercise response in mice. Sci Rep 9: 20120, 2019. Publisher Link

    Jan. 17, 2020

  • Shen MC, Zhao X, Siegal GP, Desmond R, Hardy RW. Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice. PLoS One 9: 1–12, 2014. Publisher Link

    Jan. 17, 2020

  • Grinman DY, Careaga VP, Wellberg EA, Dansey M V., Kordon EC, Anderson SM, Maier MS, Burton G, Maclean PS, Rudolph MC, Pecci A. Liver X receptor-? activation enhances cholesterol secretion in lactating mammary epithelium. Am J Physiol - Endocrinol Metab 316: E1136–E1145, 2019. Publisher Link

    Jan. 17, 2020

  • Denisova EI, Kozhevnikova V V, Bazhan NM, Makarova EN. Sex?specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring. FEBS Open Bio 10: 96–106, 2020. Publisher Link

    Jan. 17, 2020

  • Miller AC, Polgreen LA, Segre EM, Polgreen PM. Variations in Marginal Taste Perception by Body Mass Index Classification: A Randomized Controlled Trial. J Acad Nutr Diet 120: 45–52, 2019. Publisher Link

    Jan. 17, 2020

    • 2019 Journal Club Articles

  • Daly M, Sutin AR, Robinson E. Perceived Weight Discrimination Mediates the Prospective Association Between Obesity and Physiological Dysregulation: Evidence From a Population-Based Cohort. Psychol. Sci. (2019). Publisher Link

    Nov. 1, 2019

  • Michael Anson R, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci U S A 100: 6216–6220, 2003. Publisher Link

    Oct. 25, 2019

  • Alexander N, Illius S, Stalder T, Wankerl M, Muehlhan M, Kirschbaum C. Serotonin transporter gene methylation predicts long-term cortisol concentrations in hair. Psychoneuroendocrinology 106: 179–182, 2019. Publisher Link

    Oct. 25, 2019

  • Volek JS, Freidenreich DJ, Saenz C, Kunces LJ, Creighton BC, Bartley JM, Davitt PM, Munoz CX, Anderson JM, Maresh CM, Lee EC, Schuenke MD, Aerni G, Kraemer WJ, Phinney SD. Metabolic characteristics of keto-adapted ultra-endurance runners. Metabolism 65: 100–110, 2016. Publisher Link

    Oct. 25, 2019

  • Castillo-Castrejon M, Jansson T, Powell TL. No evidence of attenuation of placental insulin-stimulated Akt phosphorylation and amino acid transport in obesity and gestational diabetes mellitus. Am. J. Physiol. Metab. (2019). Publisher Link

    Oct. 18, 2019

  • Yuan J, Chen C, Cui J, Lu J, Yan C, Wei X, Zhao X, Li N, Li S, Xue G, Cheng W, Li B, Li H, Lin W, Tian C, Zhao J, Han J, An D, Zhang Q, Wei H, Zheng M, Ma X, Li W, Chen X, Zhang Z, Zeng H, Ying S, Wu J, Yang R, Liu D. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae. Cell Metab 30: 675-688.e7, 2019. Publisher Link

    Oct. 18, 2019

  • Henkel J, Alfine E, Saín J, Jöhrens K, Weber D, Castro JP, König J, Stuhlmann C, Vahrenbrink M, Jonas W, Kleinridders A, Püschel GP. Soybean oil-derived poly-unsaturated fatty acids enhance liver damage in NAFLD induced by dietary cholesterol. Nutrients 10, 2018. Publisher Link

    Oct. 18, 2019

  • Neacsu M, Fyfe C, Horgan G, Johnstone AM. Appetite control and biomarkers of satiety with Vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: A randomized crossover trial. Am J Clin Nutr 100: 548–558, 2014. Publisher Link

    Oct. 18, 2019

  • Boucsein A, Rizwan MZ, Tups A. Hypothalamic leptin sensitivity and health benefits of time-restricted feeding are dependent on the time of day in male mice. FASEB J 3: fj.201901004R, 2019. Publisher Link

    Sept. 27, 2019

  • Sierau S, Glaesmer H, Klucken T, Stalder T. Hair cortisol, lifetime traumatic experiences and psychopathology in unaccompanied refugee minors. Psychoneuroendocrinology 104: 191–194, 2019. Publisher Link

    Sept. 20, 2019

  • Tinsley GM, Moore ML, Graybeal AJ, Paoli A, Kim Y, Gonzales JU, Harry JR, VanDusseldorp TA, Kennedy DN, Cruz MR. Time-restricted feeding plus resistance training in active females: a randomized trial. Am J Clin Nutr 110: 628–640, 2019. Publisher Link

    Sept. 20, 2019

  • Chagwedera DN, Ang QY, Bisanz JE, Leong YA, Ganeshan K, Cai J, Patterson AD, Turnbaugh PJ, Chawla A. Nutrient Sensing in CD11c Cells Alters the Gut Microbiota to Regulate Food Intake and Body Mass. Cell Metab 30: 364-373.e7, 2019. Publisher Link

    Sept. 13, 2019

  • Kogan M, Klempfner R, Lotan D, Wasserstrum Y, Goldenberg I, Segal G. Low ALT blood levels are associated with lower baseline fitness amongst participants of a cardiac rehabilitation program. J Exerc Sci Fit 16: 1–4, 2018. Publisher Link

    Sept. 6, 2019

  • Radford BN, Han VKM. Offspring from maternal nutrient restriction in mice show variations in adult glucose metabolism similar to human fetal growth restriction. J. Dev. Orig. Health Dis. (2018). Publisher Link

    Sept. 6, 2019

  • Depner CM, Melanson EL, Eckel RH, Snell-Bergeon JK, Perreault L, Bergman BC, Higgins JA, Guerin MK, Stothard ER, Morton SJ, Wright KP. Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep. Curr Biol 29: 957-967.e4, 2019. Publisher Link

    Sept. 6, 2019

  • Huang T-Y, Goldsmith FR, Fuller SE, Simon J, Batdorf HM, Scott MC, Essajee NM, Brown JM, Burk DH, Morrison CD, Burke SJ, Collier JJ, Noland RC. Response of Liver Metabolic Pathways to Ketogenic Diet and Exercise Are Not Additive. 2019. Publisher Link

    Aug. 9, 2019

  • Lesage J, Del-Favero F, Leonhardt M, Louvart H, Maccari S, Vieau D, Darnaudery M. Prenatal stress induces intrauterine growth restriction and programmes glucose intolerance and feeding behaviour disturbances in the aged rat. J Endocrinol 181: 291–296, 2004. Publisher Link

    Aug. 9, 2019

  • Short SJ, Stalder T, Marceau K, Entringer S, Moog NK, Shirtcliff EA, Wadhwa PD, Buss C. Correspondence between hair cortisol concentrations and 30-day integrated daily salivary and weekly urinary cortisol measures. Psychoneuroendocrinology 71: 12–18, 2016. Publisher Link

    Aug. 2, 2019

  • Halberg N, Henriksen M, Söderhamn N, Stallknecht B, Ploug T, Schjerling P, Dela F. Effect of intermittent fasting and refeeding on insulin action in healthy men. J Appl Physiol 99: 2128–2136, 2005. Publisher Link

    Aug. 2, 2019

  • Youm Y-H, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D’Agostino D, Planavsky N, Lupfer C, Kanneganti T-DD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, Alnemri E, Dixit VD. The ketone metabolite b-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease. Nat Med 21: 263–269, 2015. Publisher Link

    Aug. 2, 2019

  • Ference BA, Ray KK, Catapano AL, Ference TB, Burgess S, Neff DR, Oliver-Williams C, Wood AM, Butterworth AS, Di Angelantonio E, Danesh J, Kastelein JJP, Nicholls SJ. Mendelian Randomization Study of ACLY and Cardiovascular Disease . N Engl J Med 380: 1033–1042, 2019. Publisher Link

    July 19, 2019

  • Chang CR, Francois ME, Little JP. Restricting carbohydrates at breakfast is sufficient to reduce 24-hour exposure to postprandial hyperglycemia and improve glycemic variability. Am J Clin Nutr 109: 1302–1309, 2019. Publisher Link

    July 19, 2019

  • Guillaume M, Riant E, Fabre A, Raymond?Letron I, Buscato M, Davezac M, Tramunt B, Montagner A, Smati S, Zahreddine R, Palierne G, Valera M, Guillou H, Lenfant F, Unsicker K, Metivier R, Fontaine C, Arnal J, Gourdy P. Selective Liver Estrogen Receptor ? Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice. Hepatol Commun 3: 908–924, 2019. Publisher Link

    July 19, 2019

  • Zhang R, Ma H, Gao Y, Wu Y, Qiao Y, Geng A, Cai C, Han Y, Zeng YA, Liu X, Ge G. Th-POK regulates mammary gland lactation through mTOR-SREBP pathway. PLoS Genet 14: 1–23, 2018. Publisher Link

    July 19, 2019

  • Gillen JB, West DW, Williamson EP, Fung HJW, Moore DR. Low-Carbohydrate Training Increases Protein Requirements of Endurance Athletes. Med Sci Sport Exerc : 1, 2019. Publisher Link

    July 12, 2019

  • Garcia-Leon MA, Peralta-Ramirez MI, Arco-Garcia L, Romero-Gonzalez B, Caparros-Gonzalez RA, Saez-Sanz N, Santos-Ruiz AM, Montero-Lopez E, Gonzalez A, Gonzalez-Perez R. Hair cortisol concentrations in a Spanish sample of healthy adults. PLoS One 13: 1–16, 2018. Publisher Link

    July 12, 2019

  • Eskenazi B, Marks AR, Catalano R, Bruckner T, Toniolo PG. Low birthweight in New York city and upstate New York following the events of September 11th. Hum Reprod 22: 3013–3020, 2007. Publisher Link

    June 14, 2019

  • Togo J, Hu S, Li M, Niu C, Speakman JR. Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: Liquid or solid. Mol Metab : 1–11, 2019. Publisher Link

    June 14, 2019

  • Sinha R, Gu P, Hart R, Guarnaccia JB. Food craving, cortisol and ghrelin responses in modeling highly palatable snack intake in the laboratory. Physiol Behav 208: 112563, 2019. Publisher Link

    June 14, 2019

  • Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJY, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. A conserved NAD + binding pocket that regulates protein-protein interactions during aging. Science (80- ) 355: 1312–1317, 2017. Publisher Link

    June 7, 2019

  • Keleidari B, Mahmoudieh M, Mofrad RM, Shahabi S, Sheikhbahaei E. Gastroileostomy for controlling body weight and lipid profile: An experimental rat model. Obes Med 15: 100096, 2019. Publisher Link

    June 7, 2019

  • Jia J, Dou P, Gao M, Kong X, Li C, Liu Z, Huang T. Assessment of Causal Direction Between Gut Microbiota-Dependent Metabolites and Cardiometabolic Health: A bi-Directional Mendelian Randomisation Analysis. Diabetes : db190153, 2019. Publisher Link

    June 7, 2019

  • Cokorinos EC, Delmore J, Reyes AR, Albuquerque B, Kjøbsted R, Jørgensen NO, Tran JL, Jatkar A, Cialdea K, Esquejo RM, Meissen J, Calabrese MF, Cordes J, Moccia R, Tess D, Salatto CT, Coskran TM, Opsahl AC, Flynn D, Blatnik M, Li W, Kindt E, Foretz M, Viollet B, Ward J, Kurumbail RG, Kalgutkar AS, Wojtaszewski JFP, Cameron KO, Miller RA. Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. Cell Metab 25: 1147-1159.e10, 2017. Publisher Link

    June 7, 2019

  • Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T. Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest 2019. Publisher Link

    May 31, 2019

  • Perez-Garcia V, Fineberg E, Wilson R, et al. Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018;555(7697):463-468. Publisher Link

    March 22, 2019

  • Ortiz LA, Quan A, Weinberg A, Baum M. Effect of prenatal dexamethasone on rat renal development. Kidney Int. 2001;59(5):1663-1669. Publisher Link

    March 22, 2019

  • Gouvêa AL, Martinez CG, Kurtenbach E. Determining Maximal Muscle Strength in Mice. J Strength Cond Res. 2018;00(00):1. Publisher Link

    March 22, 2019

  • Hall KD. Ultra-processed diets cause excess calorie intake and weight gain: A one-month inpatient randomized controlled trial of ad libitum food intake. NutriXiv. 2019. Publisher Link

    March 22, 2019

  • Graham AM, Rasmussen JM, Entringer S, et al. Maternal Cortisol Concentrations During Pregnancy and Sex-Specific Associations With Neonatal Amygdala Connectivity and Emerging Internalizing Behaviors. Biol Psychiatry. 2019;85(2):172-181. doi:10.1016/j.biopsych.2018.06.023. Publisher Link

    March 15, 2019

  • Wharfe MD, Mark PJ, Waddell BJ. Circadian variation in placental and hepatic clock genes in rat pregnancy. Endocrinology. 2011;152(9):3552-3560. doi:10.1210/en.2011-0081. Publisher Link

    March 15, 2019

  • Pattison KL, Kraschnewski JL, Lehman E, et al. Breastfeeding initiation and duration and child health outcomes in the first baby study. Prev Med (Baltim). 2019;118(March 2018):1-6. doi:10.1016/j.ypmed.2018.09.020. Publisher Link

    March 8, 2019

  • Weir T, Barbour LA, Johnson LK, et al. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018;9(1):1-12. doi:10.1038/s41467-018-06929-0. Publisher Link

    March 8, 2019

  • Høgild ML, Bak AM, Pedersen SB, et al. Growth hormone signaling and action in obese versus lean human subjects. Am J Physiol Metab. 2019;316(2):E333-E344. doi:10.1152/ajpendo.00431.2018. Publisher Link

    March 1, 2019

  • Chen Z, He P, Ding X, Huang Y, Gu H, Ni X. PPAR? stimulates expression of L-type amino acid and taurine transporters in human placentas: The evidence of PPAR? regulating fetal growth. Sci Rep. 2015;5(December 2014):1-13. doi:10.1038/srep12650. Publisher Link

    March 1, 2019

  • Herrick K, Phillips DIW, Haselden S, et al. Maternal Consumption of a High-Meat , Low- Carbohydrate Diet in Late Pregnancy : Relation to Adult Cortisol Concentrations in the Offspring. 2003;88(8):3554-3560. doi:10.1210/jc.2003-030287. Publisher Link

    March 1, 2019

  • Mitchell SJ, Bernier M, Mattison JA, et al. Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories. Cell Metab. 2019;29(1):221-228.e3. doi:10.1016/j.cmet.2018.08.011. Publisher Link

    Feb. 22, 2019

  • Falduto MT, Czerwinski SM, Hickson RC. Glucocorticoid-induced muscle atrophy prevention by exercise in fast-twitch fibers. J Appl Physiol. 2017;69(3):1058-1062. doi:10.1152/jappl.1990.69.3.1058. Publisher Link

    Feb. 22, 2019

  • Ear PH, Chadda A, Gumusoglu SB, et al. Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring. Cell Rep. 2019;26(4):969-983.e4. doi:10.1016/j.celrep.2019.01.007. Publisher Link

    Feb. 22, 2019

  • Ebbeling CB, Feldman HA, Klein GL, et al. Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial. Bmj. 2018;363:k4583. doi:10.1136/BMJ.K4583. Publisher Link

    Feb. 15, 2019

  • Rouleau G, Karpati G, Carpenter S, Soza M, Prescott S, Holland P. Glucocorticoid excess induces preferential depletion of myosin in denervated skeletal muscle fibers. Muscle Nerve. 1987;10(5):428-438. doi:10.1002/mus.880100509. Publisher Link

    Feb. 8, 2019

  • Kim W, Deik A, Gonzalez C, et al. Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD+ Recycling. Cell Metab. 2019;0(0):1-15. doi:10.1016/j.cmet.2018.12.023. Publisher Link

    Feb. 8, 2019

  • Nishiumi S, Yoshida M, Kawano Y, et al. b-Hydroxybutyrate Protects Hepatocytes Against Endoplasmic Reticulum Stress in a Sirtuin 1-Independent Manner. Arch Biochem Biophys. 2019;663(January):220-227. doi:10.1016/j.abb.2019.01.020. Publisher Link

    Feb. 8, 2019

  • Patel, S. et al. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans. Cell Metab. 1–12 (2019). Publisher Link

    Jan. 25, 2019

  • Niu, X. T. et al. Maternal high fat diet programs hypothalamic-pituitary-adrenal function in adult rat offspring. Psychoneuroendocrinology 102, 128–138 (2019). Publisher Link

    Jan. 25, 2019

  • Barbazanges, A., Piazza, P. V., Le Moal, M. & Maccari, S. Maternal Glucocorticoid Prenatal Stress Secretion Mediates Effects of. J. Neurosci. 16, 3943–3949 (1996). Publisher Link

    Jan. 25, 2019

  • Dalle, H. et al. Adipocyte glucocorticoid receptor deficiency promotes adipose tissue expandability and improves the metabolic profile under corticosterone exposure. Diabetes 1–13 (2018). Publisher Link

    Jan. 25, 2019

    • 2018 Journal Club Articles

  • Gilson, H. et al. Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy. Endocrinology 148, 452–460 (2007). Publisher Link

    Oct. 12, 2018

  • Louden, E., Chi, M. M. & Moley, K. H. Crosstalk between the AMP-activated kinase and insulin signaling pathways rescues murine blastocyst cells from insulin resistance. Reproduction 136, 335–344 (2008). Publisher Link

    Oct. 12, 2018

  • González-García, I. et al. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. Cell Rep. 25, 413–423.e5 (2018). Publisher Link

    Oct. 12, 2018

  • Meoli, L. et al. Non-alcoholic Fatty Liver Disease and Gastric Bypass Surgery Regulate Serum And Hepatic Levels of Pyruvate Kinase Isoenzyme M2. Am. J. Physiol. Endocrinol. Metab. 20, 20 (2018). Publisher Link

    Oct. 12, 2018

  • Akkad, H. et al. Vamorolone treatment improves skeletal muscle outcome in a critical illness myopathy rat model. Acta Physiol. e13172 (2018). doi:10.1111/apha.13172 Publisher Link

    Oct. 12, 2018

  • Cirulli, E. T. et al. Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk. Cell Metab. 1–13 (2018). doi:10.1016/j.cmet.2018.09.022 Publisher Link

    Oct. 12, 2018

  • Muñiz Pedrogo, D. A. et al. Gut Microbial Carbohydrate Metabolism Hinders Weight Loss in Overweight Adults Undergoing Lifestyle Intervention With a Volumetric Diet. Mayo Clin. Proc. 93, 1104–1110 (2018). Publisher Link

    Aug. 17, 2018

  • Ben-Zvi, D. et al. Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species. Cell Metab. 28, 310–323.e6 (2018). Publisher Link

    Aug. 17, 2018

  • Macedo, A. G. et al. Time-course changes of catabolic proteins following muscle atrophy induced by dexamethasone. Steroids 107, 30–36 (2016). Publisher Link

    Aug. 17, 2018

  • Krishnan, S. et al. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes. Am. J. Clin. Nutr. 108, 266–278 (2018). Publisher Link

    Aug. 17, 2018

  • Langdown, M. L. & Sugden, M. C. Enhanced placental GLUT1 and GLUT3 expression in dexamethasone-induced fetal growth retardation. Mol. Cell. Endocrinol. 185, 109–117 (2001). Publisher Link

    Aug. 17, 2018

  • Danese, A. et al. Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease. Arch. Pediatr. Adolesc. Med. 163, 1135–1143 (2009). Publisher Link

    Aug. 17, 2018

  • Gokulakrishnan, G., Estrada, I. J., Sosa, H. A. & Fiorotto, M. L. In utero glucocorticoid exposure reduces fetal skeletal muscle mass in rats independent of effects on maternal nutrition. AJP Regul. Integr. Comp. Physiol. 302, R1143–R1152 (2012). Publisher Link

    Aug. 3, 2018

  • Sutton, E. F. et al. Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes. Cell Metab. 27, 1212–1221.e3 (2018). Publisher Link

    Aug. 3, 2018

  • Reynolds, C. M., Vickers, M. H., Harrison, C. J., Segovia, S. A. & Gray, C. Maternal high fat and/or salt consumption induces sex specific inflammatory and nutrient transport in the rat placenta. Physiol. Rep. 3, 1–10 (2015). Publisher Link

    Aug. 3, 2018

  • Zemva, J. et al. Central FoxO3a and FoxO6 expression is downregulated in obesity induced diabetes but not in aging. Exp. Clin. Endocrinol. Diabetes 120, 340–350 (2012). Publisher Link

    Aug. 3, 2018

  • Taylor, R. et al. Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for ? Cell Recovery. Cell Metab. 0, 1–10 (2018). Publisher Link

    Aug. 3, 2018

  • Hopkins BD, Pauli C, Du X, et al. Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature. 2018;560(7719):499-503. Publisher Link

    July 20, 2018

  • Short, K. R., Bigelow, M. L. & Nair, K. S. Short-term prednisone use antagonizes insulin’s anabolic effect on muscle protein and glucose metabolism in young healthy people. AJP Endocrinol. Metab. 297, E1260–E1268 (2009). Publisher Link

    July 20, 2018

  • Miller, T., Mull, S., Aragon, A. A., Krieger, J. & Schoenfeld, B. J. Resistance training combined with diet decreases body fat while preserving lean mass independent of resting metabolic rate: A randomized trial. Int. J. Sport Nutr. Exerc. Metab. 28, 46–54 (2018). Publisher Link

    July 20, 2018

  • Seelig, E. et al. Metformin prevents metabolic side effects during systemic glucocorticoid treatment. Eur. J. Endocrinol. 176, 349–358 (2017). Publisher Link

    July 20, 2018

  • d’Avignon, D. A. et al. Hepatic ketogenic insufficiency reprograms hepatic glycogen metabolism and the lipidome. JCI Insight 3, (2018). Publisher Link

    June 29, 2018

  • Singh, A., Zapata, R. C., Pezeshki, A., Reidelberger, R. D. & Chelikani, P. K. Inulin fiber dose-dependently modulates energy balance, glucose tolerance, gut microbiota, hormones and diet preference in high-fat fed male rats. J. Nutr. Biochem. 1072–1074 (2018). doi:10.1016/j.jnutbio.2018.05.017 Publisher Link

    June 29, 2018

  • Song, L. et al. Prenatal high-fat diet alters placental morphology, nutrient transporter expression, and mtorc1 signaling in rat. Obesity 25, 909–919 (2017). Publisher Link

    June 29, 2018

  • Hasan, A. U. et al. PPAR? Activation Mitigates Glucocorticoid Receptor-Induced Excessive Lipolysis in Adipocytes via Homeostatic Crosstalk. J. Cell. Biochem. 1–26 (2017). doi:10.1002/jcb.26631 Publisher Link

    June 29, 2018

  • Brassard, D. et al. Saturated fats from butter but not from cheese increase HDL-Mediated cholesterol efflux capacity from J774 macrophages in men and women with abdominal obesity. J. Nutr. 148, 573–580 (2018). Publisher Link

    June 15, 2018

  • Altmäe, S. et al. Maternal pre-pregnancy obesity is associated with altered placental transcriptome. PLoS One 12, 1–17 (2017). Publisher Link

    June 15, 2018

  • Sengupta, S., Peterson, T. R., Laplante, M., Oh, S. & Sabatini, D. M. MTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature 468, 1100–1106 (2010). Publisher Link

    June 15, 2018

  • Tran, C. M. et al. Rapamycin blocks induction of the thermogenic program in white adipose tissue. Diabetes 65, 1–35 (2016). Publisher Link

    June 15, 2018

  • Zhang, M., Sun, W., Qian, J. & Tang, Y. Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid beta-oxidation and ketogenesis via activating XBP1 signaling in liver. Redox Biol. 16, 87–96 (2018). Publisher Link

    June 8, 2018

  • Guertin, D. A. et al. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev. Cell 11, 859–871 (2006). Publisher Link

    June 8, 2018

  • Luukkonen, P. K. et al. Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars. Diabetes Care dc180071 (2018). Publisher Link

    June 8, 2018

  • Li, Y., Moretto-Zita, M., Leon-Garcia, S. & Parast, M. M. P63 inhibits extravillous trophoblast migration and maintains cells in a cytotrophoblast stem cell-like state. Am. J. Pathol. 184, 3332–3343 (2014). Publisher Link

    May 25, 2018

  • Burke, S. J. et al. Oral Corticosterone Administration Reduces Insulitis but Promotes Insulin Resistance and Hyperglycemia in Male Nonobese Diabetic Mice. Am. J. Pathol. 187, 614–626 (2017). Publisher Link

    May 25, 2018

  • White, P. J. et al. The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase. Cell Metab. 0, 1–13 (2018). Publisher Link

    May 25, 2018

  • Liang, X. H. et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402, 672–675 (1999). Publisher Link

    May 11, 2018

  • Stanford, K. I. et al. 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake. Cell Metab. 27, 1111–1120.e3 (2018). Publisher Link

    May 11, 2018

  • Lancaster, G. I. et al. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism. Cell Metab. 1–15 (2018). doi:10.1016/j.cmet.2018.03.014 Publisher Link

    May 4, 2018

  • Bahrami-Nejad, Z. et al. A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation. Cell Metab. 27, 854–868.e8 (2018). Publisher Link

    May 4, 2018

  • Khera, A. V. et al. Genome - wide polygenic score to identify a monogenic risk - equivalent for coronary disease. bioRxiv (2017). doi:10.1101/218388 Publisher Link

    April 20, 2018

  • Ahmadi, M. A., Zar, A., Krustrup, P. & Ahmadi, F. Testosterone and cortisol response to acute intermittent and continuous aerobic exercise in sedentary men. Sport Sci. Health 14, 1–8 (2017). Publisher Link

    April 20, 2018

  • He, M. et al. Placental findings associated with maternal obesity at early pregnancy. Pathol. Res. Pract. 212, 282–287 (2016). Publisher Link

    April 20, 2018

  • Ravnskov, U. et al. Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: A systematic review. BMJ Open 6, 1–8 (2016). Publisher Link

    April 20, 2018

  • Hudgins, L. C. et al. Young, healthy South Asians have enhanced lipogenic sensitivity to dietary sugar. Clin. Endocrinol. (Oxf). 86, 361–366 (2017). Publisher Link

    April 6, 2018

  • Cameron, M., Camic, C. L., Doberstein, S., Erickson, J. L. & Jagim, A. R. The acute effects of a multi-ingredient pre-workout supplement on resting energy expenditure and exercise performance in recreationally active females. J. Int. Soc. Sports Nutr. 15, 1 (2018). Publisher Link

    April 6, 2018

  • Lin, Y., Zhuo, Y., Fang, Z. F., Che, L. Q. & Wu, D. Effect of maternal dietary energy types on placenta nutrient transporter gene expressions and intrauterine fetal growth in rats. Nutrition 28, 1037–1043 (2012). Publisher Link

    April 6, 2018

  • Benson, T. W. et al. A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome. Lab. Invest. (2018). doi:10.1038/s41374-018-0038-3 Publisher Link

    April 6, 2018

  • Shariatpanahi, Z. V., Shariatpanahi, M. V., Shahbazi, S., Hossaini, A. & Abadi, A. Effect of Ramadan fasting on some indices of insulin resistance and components of the metabolic syndrome in healthy male adults. Br. J. Nutr. 100, 147–151 (2008). Publisher Link

    April 6, 2018

  • Pereira, M. G. et al. Comparative analysis of muscle hypertrophy models reveals divergent gene transcription profiles and points to translational regulation of muscle growth through increased mTOR signaling. Front. Physiol. 8, 1–11 (2017). Publisher Link

    March 23, 2018

  • Heerwagen, M. J. R. et al. Placental lipoprotein lipase activity is positively associated with newborn adiposity. Placenta 64, 53–60 (2018). Publisher Link

    March 23, 2018

  • Thuzar, M. et al. Glucocorticoids suppress brown adipose tissue function in humans: A double-blind placebo-controlled study. Diabetes, Obes. Metab. 840–848 (2017). Publisher Link

    March 23, 2018

  • Shimobayashi, M. et al. Insulin resistance causes inflammation in adipose tissue. J. Clin. Invest. (2018). Publisher Link

    March 23, 2018

  • Anway M, D; Cupp A, Uzumcu S, Skinner M, K M. Epigenetic Transgenerational Action of Endocrine Disruptors and Male Fertility. Science 2005;308:1466–9. Publisher Link

    March 16, 2018

  • Wang Y, Liu Z, Han Y, Xu J, Huang W, Li Z. Medium Chain Triglycerides enhances exercise endurance through the increased mitochondrial biogenesis and metabolism. PLoS One 2018;13:1–11. Publisher Link

    March 16, 2018

  • Miyajima K, Teoh S, Yamashiro H, et al. Effects on Glycemic Control in Impaired Wound Healing in Spontaneously Diabetic Torii (SDT) Fatty Rats. Med Arch 2018;72:4. Publisher Link

    March 16, 2018

  • Zhang P, Zhu D, Zhang Y, et al. Synergetic Effects of Prenatal and Postnatal High Sucrose Intake on Glucose Tolerance and Hepatic Insulin Resistance in Rat Offspring. Mol Nutr Food Res 2018;1700771:1700771. Publisher Link

    March 16, 2018

  • Poff AM, Ari C, Seyfried TN, D’Agostino DP. The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer. PLoS One 2013;8. Publisher Link

    March 16, 2018

  • Hasan AU, Ohmori K, Hashimoto T, et al. PPAR? Activation Mitigates Glucocorticoid Receptor-Induced Excessive Lipolysis in Adipocytes via Homeostatic Crosstalk. J Cell Biochem 2017:1–26. Publisher Link

    Feb. 23, 2018

  • Jang C, Hui S, Lu W, et al. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab 2018;27:351–361.e3. Publisher Link

    Feb. 23, 2018

  • Mayer C, Acosta-Martinez M, Dubois SL, et al. Timing and completion of puberty in female mice depend on estrogen receptor -signaling in kisspeptin neurons. Proc Natl Acad Sci 2010;107:22693–22698. Publisher Link

    Feb. 16, 2018

  • Hu Y, Semova I, Sun X, et al. Fructose and glucose regulate mammalian target of rapamycin complex 1 and can activate lipogenic gene expression via distinct pathways. J Biol Chem 2017;293:jbc.M117.782557. Publisher Link

    Feb. 16, 2018

  • Chowdhury EA, Richardson JD, Tsintzas K, Thompson D, Betts JA. Postprandial Metabolism and Appetite Do Not Differ between Lean Adults that Eat Breakfast or Morning Fast for 6 Weeks. J Nutr 2018;148:13–21. Publisher Link

    Feb. 16, 2018

  • Antonio J, Ellerbroek A, Evans C, Silver T, Peacock CA. High protein consumption in trained women: bad to the bone? J Int Soc Sports Nutr 2018;15:6. Publisher Link

    Feb. 16, 2018

  • Rosqvist F, Iggman D, Kullberg J, et al. Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans. Diabetes 2014;63:2356–2368. Publisher Link

    Feb. 16, 2018