Welcome to the Bridges Lab

We are interested in the factors which cause obesity, the mechanisms by which this happens and how interventions in this pathway can alleviate obesity or its associated diseases. Our group uses a variety of model systems including cell culture, yeast, flies and mice to understand the signaling and metabolic pathways which are involved in these processes. We then use modern molecular biology, genetic and pharmacological tools to manipulate and learn more about the physiology of obesity.
Positions Available
Graduate Research Assistant
Dr. Bridges is developing and evaluating an AI-based tool that generates competency-based clinical case studies and provides rubric-based feedback on student responses. This project, funded through the Center for Academic Innovation, will test whether AI can deliver feedback comparable in quality to an experienced instructor. If it works, it could give students rapid, actionable feedback on case studies at scale. Working closely with Dr. Bridges over the 2026–27 academic year, you would:
- Review AI-generated case studies and rate their difficulty, correctness, and clinical relevance
- Help compare cases and feedback generated by different AI models (Claude, OpenAI, UM-GPT)
- Support testing of the automatic grading function against instructor "gold-standard" grading
- Assist with concordance evaluation and iterating on the grading instructions
- Contribute to a pilot Canvas integration
- Qualifications
- A current MS or MPH student in Nutritional Sciences, ideally a dietitian-in-training
- Solid grounding in clinical nutrition
- Careful, detail-oriented, and reliable with independent work
- Interest in AI in health professions education is a plus
- Required Skills
- An ability to apply rubrics and clinical judgment consistently to case study responses. Should have strong written communication and attention to detail. Comfort with data or light technical tools (e.g., spreadsheets, and openness to learning a bit of API/coding work) is welcome but not required.
- Responsibilities
- The person will review AI-generated case studies and rate their difficulty, correctness, and clinical relevance. They will help compare cases and feedback generated by different AI models (Claude, OpenAI, UM-GPT). You will support testing of the automatic feedback function against instructor "gold-standard" feedback. Finally, you will assist with evaluation and iterating on the grading instructions
Date Posted: July 20, 2026
- Haijing Sun, Margaret Rabotnick, Sofia Nicastro, Daniel Robinson, Jami Josefson, Karyna Caal, Aika Noguchi, Lindsay Ellsworth, Dave Bridges and Brigid Gregg. Preserving RNA quality when freezing of human milk samples must occur before extraction: Validation of methods utilized in a multi-center cohort study 2026. Journal of Mammary Gland Biology and Neoplasia Details Publisher Link
- Amy Zhao, Haijing Sun, Leiyi Yan, Oyewali Shiyanbola, Dave Bridges and Brigid Gregg. Lactational Western-Style Fat Exposure in Mice Programs Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Male Offspring 2026. Molecular Nutrition & Food Research 70(8):e70468 Details Publisher Link
- Erwei Li, Yangmian Yuan, Haijing Sun, Khushi Patel, Nan Zhang, Soumya Nagesh, Juan Aristizabal-Henao, Michael Kiebish, Christopher Jacobs, Dave Bridges, Brigid Gregg and Evan Rosen. Oxytocin signaling in adipocytes is required for normal milk fat production Cell Metabolism 16:S1550-4131(26)0 Details Publisher Link
- Stephanie Eid, Pongrat Jaisil, Kai Guo, John Haynes, Crystal Pacut, Diana Rigan, Andrew Carter, Samuel Teener, Bhumsoo Kim, Chloe Kiriluk, William Lentz, Cameron Miller, Ian Webber-Davis, Haley McQuown, Dai-Gyu Wang, Adam Patterson, Emily Koubek, Dave Bridges, Junguk Hur, Jacob Meyer and Eva Feldman. Ketogenic Diet and Exercise Improve Peripheral Neuropathy in a Mouse Model of Metabolic Syndrome 2016. Diabetes Details Publisher Link
- Treyton Carr, Irit Hochberg and Dave Bridges. Differential Metabolic Signatures of Cushing's Disease Patients Dependent on their Obesity Status 2026. medRxiv Details Publisher Link Preprint
Click here for a list of papers.
- Using mixed linear models for repeated measures
June 3, 2026
- mTORC1 and its Role in Nutrient Homeostasis
January 25, 2026
- Fellowship Workshop Materials
May 16, 2025
- Bayesian Approaches
March 27, 2025
- Does GDF15 absence affect pregnancy in mice?
January 27, 2025
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2026 Journal Club Articles
Feb. 23, 2026
Feb. 16, 2026
Jan. 26, 2026
2025 Journal Club Articles
Nov. 20, 2025
Nov. 6, 2025
Click here for a list of journal club articles.