Nicole Poritsanos

Position
Postdoctoral Research Fellow, Department of Physiology, University of Tennesee Health Science Center from 2013-09-16 to 2014-04-15 (Sept. 16, 2013 to April 15, 2014)
Degrees
B.Sc. (Microbiology, University of Manitoba), awarded 2003
M.Sc. (Microbiology, University of Manitoba), awarded 2005
Ph.D. (Physiology, University of Manitoba), awarded 2011
Photo of Nicole Poritsanos

Bio

To investigate the mechanisms involved in the developmental regulation of the adipose tissue by the mTORC1 pathway using in vitro and in vivo models of TSC1/2 deficiency. Understanding these mechanism(s) will contribute to the advancement of therapeutic interventions for the prevention and reversal of adipogenesis in obesity.

Publications

  1. Nicole Poritsanos, Pei San Lew, J. Fischer, C. Mobbs, J. Nagy, Davie Wong, U. Rüther and Tooru Mizuno. Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice. 2011. Nutrition & Diabetes 1:e19 Details Publisher Link
  2. Arnold Leckstrom, Pei San Lew, Nicole Poritsanos and Tooru Mizuno. Central melanocortin receptor agonist reduces hepatic lipogenic gene expression in streptozotocin-induced diabetic mice. 2011. Life sciences 88(15-16):664-9 Details Publisher Link
  3. Arnold Leckstrom, Pei San Lew, Nicole Poritsanos and Tooru Mizuno. Treatment with a melanocortin agonist improves abnormal lipid metabolism in streptozotocin-induced diabetic mice. 2011. Neuropeptides 45(2):123-9 Details Publisher Link
  4. Nicole Poritsanos, Pei San Lew and Tooru Mizuno. Relationship between blood glucose levels and hepatic Fto mRNA expression in mice. 2010. Biochemical and biophysical research communications 400(4):713-7 Details Publisher Link
  5. Nicole Poritsanos, Tooru Mizuno, M. Lautatzis and Maria Vrontakis. Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. 2009. International journal of obesity 33(12):1381-9 Details Publisher Link
  6. Nicole Poritsanos, Davie Wong, Maria Vrontakis and Tooru Mizuno. Regulation of hepatic PPARgamma2 and lipogenic gene expression by melanocortin. 2008. Biochemical and biophysical research communications 376(2):384-8 Details Publisher Link