SOP - BVT.2733

OSEH Recommendations/Findings for BVT.2733

Potential hazards of this material are unknown. This may be due to lack of information provided on the specific drug and/or it may be investigational/experimental/novel in nature. Therefore, limited or no information regarding potential toxicity was found. Thus, it is always prudent to handle as potentially hazardous agents. Caution should be exercised when handling and preparing solutions. The lab must use a biological safety cabinet during reconstitution and dilution of this material as well as use proper techniques to prevent contamination onto work surfaces. Personnel preparing this agent should wear double nitrile or latex gloves, safety glasses and a lab coat. All needles, syringes, vials, ampules and other materials which have come in contact with this agent should be segregated and disposed as hazardous waste. Unless evidence is provided to support a different course of action, it is EHS’s policy to house animals in the ULAM Animal Containment Housing facilities for a period of 3 days after each administration. After this time, the animals must be changed to a clean cage and can then be moved to standard animal housing facility. All waste materials, including bedding and carcasses must be collected and disposed through EHS HazMat while the animals are in Containment Housing. EHS HazMat (3‐4568) must be contacted prior to the commencement of this experiment to ensure proper waste containers are available for collection of this material. This policy is designed to reduce the potential exposure of animal care technicians and cage wash personnel to hazardous materials that may contaminate the dirty bedding. EHS can reevaluate housing requirements if the lab can provide information indicating that the material(s) are metabolized to a non‐hazardous substance and poses little risk to animal care personnel. Follow the link below for help on the preparation of chemical waste for collection: http://www.ehs.umich.edu/pdf/Chemical_Waste_Poster.pdf