PCR Amplification of DNA: Difference between revisions

No edit summary
mNo edit summary
Line 15: Line 15:


*Run PCR Program.  Normally use touchdown PCR ('''DAVETD''') as follows:
*Run PCR Program.  Normally use touchdown PCR ('''DAVETD''') as follows:
##1 min at 94
#1 min at 94
##30s at 65
#30s at 65
##2 min/kb at 72
#2 min/kb at 72
##30s at 94
#30s at 94
##30s at 63 then -0.5/cycle
#30s at 63 then -0.5/cycle
##2 min/kb at 72
#2 min/kb at 72
##Repeat steps 4-6 28 times
#Repeat steps 4-6 28 times
##30s at 94
#30s at 94
##30s at 45
#30s at 45
##11 min at 72
#11 min at 72
##hold at 4 until ready
#hold at 4 until ready
*Purify PCR product if necessary using Qiagen kit (Add 5x PB)
*Purify PCR product if necessary using Qiagen kit (Add 5x PB)