Designing and Preparing dsRNA: Difference between revisions

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===Template Preparation===
===Template Preparation===
*set up a 250 uL PCR reaction
*set up a 250 uL PCR reaction
**50 uL 10X KOD byffer
**25 uL 10X KOD buffer
**50 uL dNTPs
**25 uL dNTPs
**30 uL MgCl (this can be adjusted to optimize PCR conditions)
**50 uL Primers (sense and antisense combined and diluted to 1 uM.  2 uL of each primer plus 196 uL of water)
**15 uL MgCl (this can be adjusted to optimize PCR conditions)
**Template (previously prepared PCR product or 1 uL of cDNA)
**Template (previously prepared PCR product or 1 uL of cDNA)
**2 uL KOD polymerase
**2 uL KOD polymerase