Immunofluoresence: Difference between revisions

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#Wash once with PBS
#Wash once with PBS
#Permeabilize for 10 min with Triton X-100 (0.1% in PBS)
#Permeabilize for 10 min with Triton X-100 (0.1% in PBS)
#Wash three times with PBS
#Wash three times with PBS (5 min each)
#Block for 1-2h with 200 uL of BSA/Ovalbumin (1% of each in PBS) blocking solution
#Block for 1-2h with 200 uL of BSA/Ovalbumin (1% of each in PBS) blocking solution
#Incubate overnight with primary antibody in blocking solution
#Incubate overnight with primary antibody in blocking solution
#Wash coverslips 3 times 10 minutes with PBS
#Wash coverslips 3 times 10 minutes with PBS (5 min each)
#Incubate in 500X secondary solution
#Incubate in 500X secondary solution
#Wash coverslips 3 times 10 minutes with PBS
#Wash coverslips 3 times 10 minutes with PBS (5 min each)
#Add 10 uL vectashield to glass slide and place cells on slide.  Fix with nail polish
#Add 10 uL vectashield to glass slide and place cells on slide.  Fix with nail polish