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Assessing isoproterenol-stimulated whole-body lipolysis in vivo

498 bytes added, 18:12, 24 July 2014
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== Assessing Isoproterenol-Stimulated Whole-Body Lipolysis ''in vivo'' ==
Background#Lipolysis is the hydrolysis of triglycerides into glycerol and free fatty acids. Lipolysis is induced through activation of beta adrenergic receptors. Isoproterenol/Isoprenaline is a non-selective beta adrenergic agonist structurally similar to adrenaline. By administering isoproterenol ''in vivo'', it is possible to artificially stimulate whole-body lipolysis and assess changes in the concentrations of the products of lipolysis (i.e., glycerol and free fatty acids) in the blood.
Note: Mice do not need to be in a fasted state prior to this test.